Auto-immuniteit

Rheumatology

Collagenoses/Connective tissue diseases

ELISA Immunoblot IFT MicroArray
nRNP / Sm * * *
nRNP70, A, C * *
Sm * * *
SS-A (Ro, 60 kDa) * * *
SS-B (La) * * *
Scl-70 * * *
Jo-1 * * *
Ribosomal P-proteins * * *
Centromeres (CENP A) * *
Centromeres (CENP B) * * *
PM-Scl75 * *
PM-Scl100 * * *
dsDNA * * *
Histones * * *
Nucleosomes * * *
ssDNA * *
Ro-52 * * *
Proliferating cell nuclear antigen (PCNA, cyclin 1) * * *
Mitosin (CENP-F) *
Ku * *
Mi-2α, Mi-2β * *
Signal recognition particle (SRP) * *
PL-7, PL-12, EJ, OJ * *
Platelet-derived growth factor receptor (PDGFR) *
Th / To *
NOR-90 * *
Fibrillarin * *
RNA polymerase III (RP155, RP11) * *
Circulating immune complexes (CIC) *
TIF1ϒ * *
MDA5 *
NXP2 *
SAE1 *
cN-1A *
DFS70 * * *

 

Rheumatoid arthritis

ELISA Immunoblot IFT MicroArray
Cyclic citrullinated peptides (CCP) *
Rheumatoid factor (RF) *
Filaggrin (RA keratin) *
Sa *
Citrullinated alpha-enolase peptide 1 (CEP-1) *

 

Antiphospholipid syndrome (APS)

ELISA Immunoblot IFT MicroArray
Cardiolipin *
β2-glycoprotein 1 *
Phosphatidylserine *

Vasculitis / Nephrology

ELISA Immunoblot IFT MicroArray
Granulocyte cytoplasm (ANCA) *
Proteinase 3 (PR3) * * *
Myeloperoxidase (MPO) * * *
Elastase * *
Cathepsin G * *
Bactericidal permeability-increasing protein (BPI) * *
Lactoferrin * *
Lysozyme *
Glomerular basement membrane (GBM) * * *
Renal tubule basement membrane *
Alveolar basement membrane *
Phospholipase A2 receptor (PLA2R) * *
Thrombospondin type-1 domain-containing protein 7A (THSD7A) *

 

Gastroenterology

Pernicious anaemia

ELISA Immunoblot IFT MicroArray
Parietal cells (PCA) * *
Intrinsic factor (IF) * *

 

Coeliac disease (gluten-sensitive enteropathy)

ELISA Immunoblot IFT MicroArray
Deamidated gliadin (GAF-3X) * * *
Endomysium (EmA) *
Tissue transglutaminase (tTG) * *

 

Chronic inflammatory bowel diseases

ELISA Immunoblot IFT MicroArray
Pancreas acini (CUZD1 and GP2) *
Intestinal goblet cells (BAk) *
Saccharomyces cerevisiae * *
DNA-bound lactoferrin (LFS-granulocytes) *

 

Autoimmune liver diseases

 

ELISA Immunoblot IFT MicroArray
Smooth muscles (SMA, type actin) *
Soluble liver antigen / liver-pancreas antigen (SLA / LP) * * *
Cytosolic liver antigen type 1 (LC-1) * * *
Liver-kidney microsomes (LKM-1) * * *
AMA M2-3E * * *
Nuclear dots *
Sp100 * *
PML * *
Nuclear membrane *
gp210 * *
p62 *
Lamins *
pANCA (granulocytes) *

 

Endocrinology

Diabetes

ELISA Immunoblot IFT MicroArray
Pancreas islets (ICA) *
Glutamic acid decarboxylase (GAD) * *
Tyrosine phosphatase (IA2) * *

 

Autoimmune thyroid diseases

ELISA Immunoblot IFT MicroArray
Thyroid peroxidase (TPO) * *
Thyroglobulin (TG) * *
TSH receptor (thyrotropin receptor) *

 

Autoimmune polyendocrinopathy / Infertility

ELISA Immunoblot IFT MicroArray
Parathyroid gland *
Adrenal cortex *
Ovary *
Placenta *
Pituitary gland *
Hypothalamus *
Spermatozoa * *
Testis / Leydig cells *
Uterus *

 

Neurology

Paraneoplastic syndrome

ELISA Immunoblot IFT MicroArray
Hu (ANNA-1) * *
Yo (PCA-1) * *
Ri (ANNA-2) * *
Amphiphysin * *
CV2 (CRMP5) * *
Ma (Ma1, Ma2 / Ta) * *
PCA-2 *
Tr (DNER) * *
ITPR1 *
CARP *
SOX1 * *
Glutamic acid decarboxylase (GAD) * * *
Titin * *
Recoverin * *
Zic4 * *

 

Receptor & membrane proteins

ELISA Immunoblot IFT MicroArray
Aquaporin-4 (NMO-IgG) *
Myelin oligodendrocyte glycoprotein (MOG) *
mGLUR5 – Flotillin *
Glutamate receptors (types NMDA and AMPA) *
GABAB receptors *
VGKC associated proteins (LGI1, CASPR2) *
DPPX *
IgLON5 *

 

Other parameters

ELISA Immunoblot IFT MicroArray
Gangliosides (GM1, GM2, GM3, GD1a, GD1b, GT1b, GQ1b) *
Myelin *
Myelin-associated glycoprotein (MAG) *
Hippocampus *
Cerebrum *
Cerebellum *
Peripheral nerves *
Spinal marrow *
Optic nerve *
Striated muscles *
Acetylcholine receptor *
GFAP *
Synaptophysin *
Neuroendothelium *

Dermatology

ELISA Immunoblot IFT MicroArray
Epidermal basement membrane (EBM) *
BP180 * *
BP230 * *
Desmosomes *
Desmoglein 1 * *
Desmoglein 3 * *
Envoplakin * *
Salt-split skin *
Transitional epithelium *
Collagen type VII * *
Tissue transglutaminase (tTG) * *
Endomysium (EmA) *
Deamidated gliadin (GAF-3X) * * *

 

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