Individuele substraten voor auto-immuniteit IIFT
Naast de gepatenteerde mozaïektechnologie die verschillende substraten in eenzelfde well combineert, bieden Biognost en EUROIMMUN u een breed gamma aan individuele substraten voor indirecte immunofluorescentie, die hun CE-IVD-markering behouden na 26 mei 2022.
- Complete kits met alle reagentia die nodig zijn voor uitvoering van de IIFT
- Universele procedure die parallelle incubatie van verschillende parameters mogelijk maakt zowel manueel als op pipettors
- Gebruiksklare reagentia (FITC, PBS en TWEEN-20 voor dilutie/wasbuffer, montagemedium) uitwisselbaar tussen kits
- Hydrofobe slides voorzien van 2D-barcode
Rheumatology
Collagenoses/Connective tissue diseases
| ELISA | Immunoblot | IFT | MicroArray | |
| Cell components (ANA) | * | |||
| nRNP / Sm | * | * | * | |
| nRNP70, A, C | * | * | ||
| Sm | * | * | * | |
| SS-A (Ro, 60 kDa) | * | * | * | |
| SS-B (La) | * | * | * | |
| Scl-70 | * | * | * | |
| Jo-1 | * | * | * | |
| Ribosomal P-proteins | * | * | * | |
| Centromeres (CENP A) | * | * | ||
| Centromeres (CENP B) | * | * | * | |
| PM-Scl75 | * | * | ||
| PM-Scl100 | * | * | * | |
| dsDNA | * | * | * | |
| Histones | * | * | * | |
| Nucleosomes | * | * | * | |
| ssDNA | * | * | ||
| Ro-52 | * | * | * | |
| Proliferating cell nuclear antigen (PCNA, cyclin 1) | * | * | * | |
| Mitosin (CENP-F) | * | |||
| Ku | * | * | ||
| Mi-2α, Mi-2β | * | * | ||
| Signal recognition particle (SRP) | * | * | ||
| PL-7, PL-12, EJ, OJ | * | * | ||
| Platelet-derived growth factor receptor (PDGFR) | * | |||
| Th / To | * | |||
| NOR-90 | * | * | ||
| Fibrillarin | * | * | ||
| RNA polymerase III (RP155, RP11) | * | * | ||
| Circulating immune complexes (CIC) | * | |||
| TIF1ϒ | * | * | ||
| MDA5 | * | |||
| NXP2 | * | |||
| SAE1 | * | |||
| cN-1A | * | * | ||
| DFS70 | * | * | * |
Rheumatoid arthritis
| ELISA | Immunoblot | IFT | MicroArray | |
| Cyclic citrullinated peptides (CCP) | * | |||
| Rheumatoid factor (RF) | * | |||
| Filaggrin (RA keratin) | * | |||
| Sa | * | |||
| Citrullinated alpha-enolase peptide 1 (CEP-1) | * |
Antiphospholipid syndrome (APS)
| ELISA | Immunoblot | IFT | MicroArray | |
| Cardiolipin | * | |||
| β2-glycoprotein 1 | * | |||
| Phosphatidylserine | * |
Vasculitis / Nephrology
| ELISA | Immunoblot | IFT | MicroArray | ChLIA | |
| Granulocyte cytoplasm (ANCA) | * | ||||
| Proteinase 3 (PR3) | * | * | * | * | |
| Myeloperoxidase (MPO) | * | * | * | ||
| Elastase | * | * | |||
| Cathepsin G | * | * | |||
| Bactericidal permeability-increasing protein (BPI) | * | * | |||
| Lactoferrin | * | * | |||
| Lysozyme | * | ||||
| Glomerular basement membrane (GBM) | * | * | * | ||
| Renal tubule basement membrane | * | ||||
| Alveolar basement membrane | * | ||||
| Phospholipase A2 receptor (PLA2R) | * | * | * | ||
| Thrombospondin type-1 domain-containing protein 7A (THSD7A) | * |
Gastroenterology
Pernicious anaemia
| ELISA | Immunoblot | IFT | MicroArray | |
| Parietal cells (PCA) | * | * | ||
| Intrinsic factor (IF) | * | * | ||
| Parietal cell antigen ATP4B (beta-subunit of H+/K+-ATPase) | * |
Coeliac disease (gluten-sensitive enteropathy)
| ELISA | Immunoblot | IFT | MicroArray | |
| Deamidated gliadin (GAF-3X) | * | * | * | |
| Endomysium (EmA) | * | |||
| Tissue transglutaminase (tTG) | * | * | * |
Chronic inflammatory bowel diseases
| ELISA | Immunoblot | IFT | MicroArray | |
| Pancreas acini (CUZD1 and GP2) | * | |||
| Intestinal goblet cells (BAk) | * | |||
| Saccharomyces cerevisiae | * | * | ||
| DNA-bound lactoferrin (LFS-granulocytes) | * |
Autoimmune liver diseases
| ELISA | Immunoblot | IFT | MicroArray | |
| Smooth muscles (SMA, type actin) | * | |||
| Soluble liver antigen / liver-pancreas antigen (SLA / LP) | * | * | * | |
| Cytosolic liver antigen type 1 (LC-1) | * | * | * | |
| Liver-kidney microsomes (LKM-1) | * | * | * | |
| AMA M2-3E | * | * | * | |
| Nuclear dots | * | |||
| Sp100 | * | * | ||
| PML | * | * | ||
| Nuclear membrane | * | |||
| gp210 | * | * | ||
| p62 | * | |||
| Lamins | * | |||
| pANCA (granulocytes) | * |
Endocrinology
Diabetes
| ELISA | Immunoblot | IFT | MicroArray | |
| Pancreas islets (ICA) | * | |||
| Glutamic acid decarboxylase (GAD) | * | * | ||
| Tyrosine phosphatase (IA2) | * | * | ||
| Zinc transporter 8 (ZnT8) | * | * |
Autoimmune thyroid diseases
| ELISA | Immunoblot | IFT | MicroArray | |
| Thyroid peroxidase (TPO) | * | * | ||
| Thyroglobulin (TG) | * | * | ||
| TSH receptor (thyrotropin receptor) | * |
Autoimmune polyendocrinopathy / Infertility
| ELISA | Immunoblot | IFT | MicroArray | |
| Parathyroid gland | * | |||
| Adrenal cortex | * | |||
| Ovary | * | |||
| Placenta | * | |||
| Pituitary gland | * | |||
| Hypothalamus | * | |||
| Spermatozoa | * | |||
| Testis / Leydig cells | * | |||
| Uterus | * |
Neurology
Paraneoplastic syndrome
| ELISA | Immunoblot | IFT | MicroArray | |
| Hu (ANNA-1) | * | * | ||
| Yo (PCA-1) | * | * | ||
| Ri (ANNA-2) | * | * | ||
| Amphiphysin | * | * | ||
| CV2 (CRMP5) | * | * | ||
| Ma (Ma1, Ma2 / Ta) | * | * | ||
| PCA-2 | * | |||
| Tr (DNER) | * | * | ||
| ITPR1 | * | |||
| CARP | * | |||
| SOX1 | * | * | ||
| Glutamic acid decarboxylase (GAD) | * | * | * | |
| Titin | * | * | ||
| Recoverin | * | * | ||
| Zic4 | * | * |
Receptor & membrane proteins
| ELISA | Immunoblot | IFT | MicroArray | |
| Aquaporin-4 (NMO-IgG) | * | |||
| Myelin oligodendrocyte glycoprotein (MOG) | * | |||
| mGLUR5 – Flotillin | * | |||
| Glutamate receptors (types NMDA and AMPA) | * | |||
| GABAB receptors | * | |||
| VGKC associated proteins (LGI1, CASPR2) | * | |||
| DPPX | * | |||
| IgLON5 | * |
Other parameters
| ELISA | Immunoblot | IFT | MicroArray | |
| Gangliosides (GM1, GM2, GM3, GD1a, GD1b, GT1b, GQ1b) | * | |||
| Myelin | * | |||
| Myelin-associated glycoprotein (MAG) | * | |||
| Hippocampus | * | |||
| Cerebrum | * | |||
| Cerebellum | * | |||
| Peripheral nerves | * | |||
| Spinal marrow | * | |||
| Optic nerve | * | |||
| Striated muscles | * | |||
| Acetylcholine receptor | * | * | ||
| Muscle-specific tyrosine kinase (MuSK) | * | |||
| GFAP | * | |||
| Synaptophysin | * | |||
| Neuroendothelium | * |
Dermatology
| ELISA | Immunoblot | IFT | MicroArray | |
| Epidermal basement membrane (EBM) | * | |||
| BP180 | * | * | ||
| BP230 | * | * | ||
| Desmosomes | * | |||
| Desmoglein 1 | * | * | ||
| Desmoglein 3 | * | * | ||
| Envoplakin | * | * | ||
| Salt-split skin | * | |||
| Transitional epithelium | * | |||
| Collagen type VII | * | * | ||
| Laminin 332 | * | |||
| Tissue transglutaminase (tTG) | * | * | ||
| Endomysium (EmA) | * | |||
| Deamidated gliadin (GAF-3X) | * | * | * |
Automatisatie
Klik hier voor meer informatie over automatisatie van al onze testen.
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